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KMID : 0383819720190020035
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Tuberculosis and Respiratory Diseases
1972 Volume.19 No. 2 p.35 ~ p.38
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The Clinical Effect of Rifampicin for Retreatment Cases for Pulmonary Tuberculosis
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Abstract
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The authors analyzed the clinical benefits and toxic effects of Rifampicin in 32
patients with prolonged previous chemotherapy without effect (5cases were
post-operative). The Rifampicin was given with one or more other anti-Tb. drugs (or 3
to 12 months. The doses were 450-600㎎ once daily or biweekly.
Sputum conversion: 14 patients had positive sputum on the begining and 7 patients
(50%) became nagative with Rifampicin treatment.
X-ray improvement There was no remarkable change noticed except slight
improvement in 7 cases.
Symptomatic improvement : Majority of cases showed a decrease of cough and sputm
souse of wellbeing, soon after the administration of Rifampicin and also showed some
gain of badyweight.
Side effects: There was no serious side effect and serious liver function disturbance
detected but one case had chill, fever and general bodyache and another case complained
of general bodyache 6 to 7 months after the Rifampicin treatment.
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KEYWORD
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